A survey of topics investigated by chemical biology methods including: transcription and translation, cell signaling, genetic and genomics, biochemical pathways, macromolecular structure, and the biosynthesis of peptides, carbohydrates, natural products, and nucleic acids. Concepts of thermodynamics and kinetics, bioconjugations and bioorthogonal chemistry will also be presented. (Same as CHEM 860, MDCM 860 and PHCH 860.) Prerequisite: Permission of instructor.