A study of the biochemical principles of macromolecular structure and function, molecular communication, and the metabolism of nutrients and xenobiotics as applied to problems of medicinal and pharmacological significance.

A study of the biochemical principles of macromolecular structure and function, biosynthesis, molecular communication, and the metabolism of nutrients and xenobiotics as applied to problems of medicinal and pharmacological significance. Prerequisite: Students must have first year professional standing in the School of Pharmacy. Students must have successfully completed MDCM 601.

This course will acquaint the pharmacy students with the current status of botanical use in the United States. A basic foundation will be provided so that the pharmacist can properly assess the appropriateness and usefulness of various phytomedicines and combinations in managing certain ailments with regard to efficacy, safety, potential toxicity, and potential herb-drug interactions. Prerequisite: Students must be admitted to the school or division of Pharmacy and have successfully completed MDCM 601 to enroll in this course.

A course designed to acquaint pharmacy students with diseases that affect and deteriorate the central nervous system. Students will learn the (1) pathophysiology of prevalent neurodegenerative disorders, (2) criteria used to diagnose and discriminate the disorder, (3) current treatments available, and (4) new therapeutic strategies (or modalities) being developed and clinically evaluated. Students will familiarize themselves with each disease topic by reading and critically assessing primary scientific literature provided by the instructor(s). Selected manuscripts will provide relevant background on the disorder and detail medicinal chemistry approaches to address its underlying etiology and/or symptomology. Assigned students will lead in class discussions of the reading materials, commenting on topics including, but not limited to, the merits of the research hypothesis, experimental design and protocols, interpretation of results, validity of the conclusions, and prospects for therapeutic translation. Discussions will follow a defined prompt provided by the instructor(s) for each topic. At the conclusion of the course, students will have a working knowledge of the cause, diagnosis, and treatment of pervasive neurodegenerative diseases, and develop skills for comprehending and critiquing scientific literature in the field of medicinal chemistry. Prerequisite: MDCM 625. Consent of Instructor.

A study, from the molecular viewpoint, of the organic substances used as medicinal agents, including consideration of their origins, chemical properties, structure-activity relationships, metabolism and mechanisms of action; this course emphasizes drugs affecting the cardiovascular and central nervous systems. Prerequisite: Students must be admitted to the school or division of Pharmacy and have successfully completed MDCM 603 to enroll in this course.

A continuation of MDCM 625 with special emphasis on anticancer, antiviral, antibacterial, antifungal, antidiabetic, anticholesterol, and steroidal drugs. Prerequisite: Students must have second year professional standing in the School of Pharmacy. Students must have successfully completed MDCM 625.

Research in medicinal chemistry. Students will be assigned to a laboratory research problem. Prerequisite: Consent of instructor.

This course encompasses original work on a laboratory problem of limited scope, honors reading assignments from medicinal chemistry literature, or in-depth discussions of assigned topics. Prerequisite: Consent of instructor.

A study of the principles of macromolecular structure and function, biosignaling, bioenergetics and metabolism, with an emphasis on the relationship between biochemistry and medicine. Prerequisite: Graduate standing or permission of instructor.

This course provides an overview of topics central to the understanding and practice of contemporary medicinal chemistry. It illustrates the interplay of anatomy and physiology with the organic-, bio- and analytical chemistry of drugs in the body. Topics covered include physiological mechanisms and disease processes; cell structure and function; basic intermediary metabolism; basic principles underlying drug action including the physicochemical properties of drugs and how these affect the interaction of drugs with living systems; chemical and biological manipulation of the absorption, distribution, metabolism and excretion of drugs and prodrugs; kinetics and inhibition of enzymes and transporters; quantitation and molecular modeling of drug binding to targets. Prerequisite: One year of organic chemistry, one semester of biochemistry, and one college-level course in biology.

A discussion of the principles of contemporary drug design with specific examples chosen from the original literature. This course covers the organic substances used as medicinal agents, including consideration of their origins, chemical properties, structure-activity relationships, metabolism and mechanisms of action. Prerequisite: Graduate standing or completion of MDCM 625 and MDCM 626.

Literature seminar for graduate students in Spring of their 2nd year. Prerequisite: Graduate students in 2nd year of program.

Reports by research students and discussions of developments in the field not covered in formal courses.

Lectures and discussion on ethical issues in the conduct of a scientific career, with emphasis on practical topics of special importance in molecular-level research in the chemical, biological, and pharmaceutical sciences. Topics will include the nature of ethics, the scientist in the laboratory, as author, grantee, reviewer, employer/employee, teacher/ student, and citizen. Discussions will focus on case histories. This course is open only to distance education students. Graded on a satisfactory/unsatisfactory basis. (Same as MDCM 801, NURO 801, P&TX 801, PHCH 801 and PHCH 802.)

This class addresses the recognized problems in rigor, reproducibility, and transparency that are plaguing modern science. Students will learn the fundamentals of hypothesis design, avoiding bias, randomization, sampling, and appropriate statistical analyses, reagent validation, among other key topics. This course also introduces principles for being an ethical, responsible, and professional research scientist. Topics include: plagiarism, fabrication and falsification of data, record keeping and data sharing, mentor/mentee and collaborative relationships, among others. The class will include a mixture of lecture, case studies and discussion. (Same as BIOL 817/CHEM 817/PHCH 817.) Prerequisite: Graduate student.

A survey of topics investigated by chemical biology methods including: transcription and translation, cell signaling, genetic and genomics, biochemical pathways, macromolecular structure, and the biosynthesis of peptides, carbohydrates, natural products, and nucleic acids. Concepts of thermodynamics and kinetics, bioconjugations and bioorthogonal chemistry will also be presented. (Same as BIOL 860, CHEM 860 and PHCH 860.) Prerequisite: Permission of instructor.

Hours and credit to be arranged.

Hours and credit to be arranged. Independent investigation of a research problem of limited scope. Prerequisite: Consent of instructor.

Presentation of a literature seminar and writing an original NIH-style research proposal concerning contemporary problems in medicinal chemistry. Prerequisite: Consent of instructor.

Hours and credit to be arranged. Original chemical research in the synthesis and development of medicinal agents, elucidation of the chemical mechanisms of drug action, drug metabolism, and drug toxicities.

This elective class will explore emerging areas of research currently impacting the pharmaceutical industry. Potential topics include; biologicals as therapeutics, drug targeting, prodrugs, nanotechnology, biological barriers, gene therapy, transporters, vaccines, intracellular drug trafficking, controlled release drug delivery, cancer therapy, analytical biotechnology and many others. The class will be team taught by PHCH faculty and guest speakers. Graded on a satisfactory/unsatisfactory basis. Prerequisite: Must be accepted to the Pharmacy Program.

This special topics course will cover key steps in developing and bringing a new drug through pharmaceutical development and regulatory approval and into commercial use. Development of both traditional small-molecule chemical drugs and biotechnology-based protein drugs will be discussed. Example topics include: (1) how does a drug candidate move from its discovery at the lab bench into clinical trials? (2) what are the key hurdles in developing a new medicine that can be produced at large-scale in a manufacturing facility? (3) why are patents and venture capital so important in drug development? Guest lecturers will provide real world perspectives including case studies. This is two-hour class that meets 8 times during the semester. Prerequisite: 1st, 2nd or 3rd professional year standing in the School of Pharmacy.

An introduction to the mathematics involved in filling prescriptions and in manufacturing pharmaceuticals. Includes an introduction to standard prescription notation and familiarization with pharmaceutical weights and measures.

Physical properties of pharmaceutical solutions and their physiological compatibility will be discussed (intermolecular interactions, energetics, colligative properties, isotonicity, pH, buffers and drug solubility). Kinetics and mechanisms of drug degradation in solution will also be introduced. Prerequisite: Students must have first year professional standing in the School of Pharmacy. Students must have successfully completed PHCH 517.

Vaccines are currently the most powerful therapeutic approach available for infectious disease and promise to become of increasing importance for a wide variety of other pathologies including cancer. This course discusses the immunological basis of vaccinology, types of vaccines currently available and in development and the process by which vaccines are made from the basic research stage through their pharmaceutical development and marketing. Ethical aspects of vaccine use will also be considered. Prerequisite: Students must have first, second or third year professional standing in the School of Pharmacy.

A discussion of the basic concepts, and some clinical applications, of pharmacokinetics, clearance concepts, extravascular dosing, and the use of pharmacokinetics in dosage regimen design and adjustment. Prerequisite: Students must be admitted to the school of Pharmacy to enroll in this course. Students must have successfully completed PHCH 517 and PHCH 518.

A study of biological barriers to drug delivery, conventional dosage forms, and new and future drug delivery strategies. Prerequisite: Students must have second year professional standing in the School of Pharmacy. Students must have successfully completed PHCH 517, PHCH 518, and PHCH 625.

A lecture-discussion course concerned with identification of the contents of physiological fluids, changes in physiological fluid content induced by disease and drugs, and therapeutic drug monitoring: case studies are presented. Prerequisite: Must be accepted to the Pharmacy Program.

Student will be assigned a suitable research project in the area of pharmaceutical analysis or pharmaceutics. Prerequisite: Consent of instructor.

This course presents discussions on physiological and disease state variables in pharmacokinetics for selected drugs and drug classes, and instructs students in the use of physiological and disease state pharmacokinetic information to develop individualized therapeutic regimens. Prerequisite: Students must be admitted to the school of Pharmacy to enroll in this course. Students must have successfully completed PHCH 625 and PHCH 626.

A student will be assigned a suitable research project in an area of pharmaceutical analysis or pharmaceutics. This course is offered regularly by the Department of Pharmaceutical Chemistry to meet the special needs of selected students, usually for one of the following two situations: (1) This course may be taken when a student has a special interest in a problem or area of limited scope and desires to pursue that study in depth under supervision of a member of the faculty. (2) This course is sometimes used as a remedial class to provide a mechanism of intensive review and study in an area of weakness. Prerequisite: Consent of instructor.

Discussions, lectures, and laboratory work designed to acquaint and provide hands on experiences to advanced undergraduate and graduate students with experimental design, methods, and approaches relevant to modern research in pharmaceutical chemistry. Prerequisite: Consent of instructor.

Communicating research proposals and experimental findings is a critical skill for scientists. Successful communication depends on clarity of thought and careful use of language. This course will use class discussions with examples and homework assignments to help prepare the graduate student to successfully communicate in both academia and industry settings. Graded on a satisfactory/unsatisfactory basis. Prerequisite: Graduate standing in PHCH or consent of the instructor.

Communicating research proposals and experimental findings is a critical skill for scientists. Successful communication depends on clarity of thought and careful use of language. This course will use class discussions with examples and homework assignments to help prepare the graduate student to successfully communicate in both academia and industry settings. Graded on a satisfactory/unsatisfactory basis. Prerequisite: This course is only open to distance education students.

This special topics course will cover key steps in developing and bringing a new drug through pharmaceutical development and regulatory approval and into commercial use. Development of both traditional small-molecule chemical drugs and biotechnology-based protein drugs will be discussed. Example topics include: (1) how does a drug candidate move from its discovery at the lab bench into clinical trials? (2) what are the key hurdles in developing a new medicine that can be produced at large-scale in a manufacturing facility? (3) why are patents and venture capital so important in drug development? Guest lecturers will provide real world perspectives including case studies. This is two-hour class that meets 8 times during the semester. Prerequisite: Graduate standing in Pharmaceutical Chemistry or a trainee of the NIH Biotech Training Grant.

The course will survey the latest technology for delivering pharmaceuticals and biologicals to reduce side effects and enhance drug efficacy. The course will survey the latest research in this area and examine more classical delivery methods. A qualitative and quantitative understanding of drug delivery practice and theory is the goal. Prerequisite: Master's or PhD candidate in Engineering, Chemistry, Medicinal Chemistry, or Pharmaceutical Chemistry (by appointment for seniors or graduate students in departments not listed).

The course will survey the latest technology for delivering pharmaceuticals and biologicals to reduce side effects and enhance drug efficacy. The course will survey the latest research in this area and examine more classical delivery methods. A qualitative and quantitative understanding of drug delivery practice and theory is the goal. Prerequisite: This course is only open to distance education students.

The course will survey the latest technology for delivering pharmaceuticals and biologicals to reduce side effects and enhance drug efficacy. The course will survey the latest research in this area and examine more classical delivery methods. A qualitative and quantitative understanding of drug delivery practice and theory is the goal. This course is only open to external non-degree seeking students. Offered in spring semesters. Prerequisite: PHCH 732.

Physical properties of pharmaceutical solutions and their physiological compatibility will be discussed (intermolecular interactions, energetics, colligative properties, isotonicity, pH, buffers and drug solubility). Kinetics and mechanisms of drug degradation in solution will also be introduced. Prerequisite: Graduate standing.

Physical properties of pharmaceutical solutions and their physiological compatibility will be discussed (intermolecular interactions, energetics, colligative properties, isotonicity, pH, buffers and drug solubility). Kinetics and mechanisms of drug degradation in solution will also be introduced. This course is only open to distance education students. Prerequisite: Graduate standing.

Physical properties of pharmaceutical solutions and their physiological compatibility will be discussed (intermolecular interactions, energetics, colligative properties, isotonicity, pH, buffers and drug solubility). Kinetics and mechanisms of drug degradation in solution will also be introduced. This course is only open to external non-degree seeking students. Offered in spring semesters.

The pharmaceutical relevance of fundamental and advanced concepts in cell biology and the molecular interactions responsible for cell and tissue functions, homeostasis in health and disease will be presented. Current analytical methods for examining cells and tissues, and molecular components important in understanding drug and protein biodistribution and metabolism will be discussed. Discussion topics will include the chemical and physical properties of small molecules, proteins, nucleic acids and lipids and their impact on cellular and subcellular structures and ultimately of either adverse or therapeutic benefit. (Same as C&PE 725.) Prerequisite: Graduate standing or consent of instructor.

The pharmaceutical relevance of fundamental and advanced concepts in cell biology and the molecular interactions responsible for cell and tissue functions, homeostasis in health and disease will be presented. Current analytical methods for examining cells and tissues, and molecular components important in understanding drug and protein biodistribution and metabolism will be discussed. Discussion topics will include the chemical and physical properties of small molecules, proteins, nucleic acids and lipids and their impact on cellular and subcellular structures and ultimately of either adverse or therapeutic benefit. Prerequisite: Graduate standing or consent of instructor.

A quantitative treatment of the processes involved with drug absorption, distribution, metabolism, and excretion in living systems.

A quantitative treatment of the processes involved with drug absorption, distribution, metabolism, and excretion in living systems. This course open only to distance education students.

A quantitative treatment of the processes involved with drug absorption, distribution, metabolism, and excretion in living systems. This course is only open to external non-degree seeking students. Offered in fall semesters.

A consideration of the structural features and driving forces that control the course of chemical reactions. Topics will include functional group chemistry: electronic structure, acid/base properties: molecular structure and properties (dipole, strain, and steric effects, inductive and resonance effects); dynamics of reactions (the major organic reaction mechanism, kinetics, energy profiles, isotope effects, linear free energy relationships), solvent effects, stereochemistry and conformation, an introduction to orbital symmetry control; basic thermodynamic and kinetic concepts; and an overview of important classes of mechanisms. This course is only open to distance education students. Prerequisite: CHEM 624 and CHEM 626.

Lectures and discussion on ethical issues in the conduct of a scientific career, with emphasis on practical topics of special importance in molecular-level research in the chemical, biological, and pharmaceutical sciences. Topics will include the nature of ethics, the scientist in the laboratory, as author, grantee, reviewer, employer/employee, teacher/ student, and citizen. Discussions will focus on case histories. This course is open only to distance education students. Graded on a satisfactory/unsatisfactory basis. (Same as MDCM 801, NURO 801, P&TX 801 and PHCH 802.)

Lectures and discussion on ethical issues in the conduct of a scientific career, with emphasis on practical topics of special importance in molecular-level research in the chemical, biological, and pharmaceutical sciences. Topics will include the nature of ethics, the scientist in the laboratory, as author, grantee, reviewer, employer/employee, teacher/ student, and citizen. Discussions will focus on case histories. This course is open only to distance education students. Graded on a satisfactory/unsatisfactory basis. (Same as PHCH 801, MDCM 801, NURO 801, and P&TX 801.)

Advanced course examining career options open to PhD scientists in the biomedical sciences, and providing preparation for the different career paths. Extensive student/faculty interaction is emphasized utilizing lectures, class discussion of assigned readings, and oral presentations. Graded on a satisfactory/unsatisfactory basis. (Same as BIOL 816 and CHEM 816.) Prerequisite: Permission of instructor.

This class addresses the recognized problems in rigor, reproducibility, and transparency that are plaguing modern science. Students will learn the fundamentals of hypothesis design, avoiding bias, randomization, sampling, and appropriate statistical analyses, reagent validation, among other key topics. This course also introduces principles for being an ethical, responsible, and professional research scientist. Topics include: plagiarism, fabrication and falsification of data, record keeping and data sharing, mentor/mentee and collaborative relationships, among others. The class will include a mixture of lecture, case studies and discussion. (Same as BIOL 817/CHEM 817/MDCM 817.) Prerequisite: Graduate student.

This course is designed to provide an understanding of the formulation and stability of small and large drug candidates in the solid state. The first two-thirds of the course will focus on small molecules, with the last third being devoted to proteins. Graded on a satisfactory/fail basis. Prerequisite: Graduate standing in PHCH or consent of the instructor.

This course is designed to provide an understanding of the formulation and stability of small and large drug candidates in the solid state. The first two-thirds of the course will focus on small molecules, with the last third being devoted to proteins. This course is open only to distance education students. Prerequisite: Graduate standing in Pharmaceutical Chemistry or consent of the instructor.

A survey of topics investigated by chemical biology methods including: transcription and translation, cell signaling, genetic and genomics, biochemical pathways, macromolecular structure, and the biosynthesis of peptides, carbohydrates, natural products, and nucleic acids. Concepts of thermodynamics and kinetics, bioconjugations and bioorthogonal chemistry will also be presented. (Same as BIOL 860, CHEM 860 and MDCM 860.) Prerequisite: Permission of instructor.

A course on equilibria in aqueous and non-aqueous systems with emphasis on solutions of interest to pharmaceutical technology. Included are association-dissociation equilibria, complexation, protein binding calculation of species concentrations, estimation of solubility and ionization constants. Methods for the determination of chemical potential in solution are presented.

A course on equilibria in aqueous and non-aqueous systems with emphasis on solutions of interest to pharmaceutical technology. Included are association-dissociation equilibria, complexation, protein binding calculation of species concentrations, estimation of solubility and ionization constants. Methods for the determination of chemical potential in solution are presented. This course is open only to distance education students.

This course is intended to be a comprehensive treatment of contemporary techniques used to validate analytical methods for the determination of drugs in the bulk form, pharmaceutical formulations, biological samples and other relevant media. The emphasis will be on chromatographic techniques reflecting the preeminent position that those techniques occupy in the field of pharmaceutical and biomedical analysis. Prerequisite: Previous or concurrent enrollment in PHCH 684.

Advanced course on pharmaceutical analysis. This course is only open to distance education students.

A course designed to emphasize the important facets of recombinant proteins and vaccines as pharmaceutical agents. Basics of protein structure and analysis will be introduced, and methods for production, isolation, and purification of recombinant proteins will be described. Potential chemical and physical degradation processes and strategies for circumventing these difficulties will be discussed. An overview of the development and formulation of vaccines and their immunological basis will be presented. Prerequisite: BIOL 600 or consent of instructor.

A course designed to emphasize the important facets of recombinant proteins and vaccines as pharmaceutical agents. Basics of protein structure and analysis will be introduced, and methods for production, isolation, and purification of recombinant proteins will be described. Potential chemical and physical degradation processes and strategies for circumventing these difficulties will be discussed. This course is only open to distance education students. An overview of the development and formulation of vaccines and their immunological basis will be presented. Prerequisite: BIOL 600 or consent of instructor.

Advanced level research in collaboration with a faculty member in pharmaceutical chemistry or related areas. This course is limited to students who are doing research, but not necessarily working toward either a master's or a doctoral degree.

Master's Thesis. This course is open only to distance education students.

Graded on a satisfactory/fail basis.

This course provides the principles of kinetic data analysis as applied to problems in pharmaceutical chemistry. Topics include the setup and solution of rate equations related to chemical reactions; simplifications and approximations in complex equation systems; isotope, solvent and salt rate effects; and diffusion and activation controlled reactions.

This course provides the principles of kinetic data analysis as applied to problems in pharmaceutical chemistry. Topics include the setup and solution of rate equations related to chemical reactions; simplifications and approximations in complex equation systems; isotope, solvent and salt rate effects; and diffusion and activation controlled reactions. This course is only open to distance education students.

A course dealing with mechanisms and chemical kinetics of drug deterioration and stabilization.

A course dealing with mechanisms and chemical kinetics of drug deterioration and stabilization. This course is only open to distance education students.

Various topics pertinent to the area of pharmaceutical chemistry will be explored. Graded on a satisfactory/unsatisfactory basis.

A seminar on the chemistry of pharmaceutical systems.

This course is open only to distance education students.

Presentations of research papers by faculty, post-doctoral research associates, and graduate students. All graduate students in the Neuroscience program participate in this seminar series throughout their period of training. Each student has to present a seminar once every semester. Presentations by students are evaluated by other graduate students and faculty at the end of each seminar. (Same as NEUS 799.) Prerequisite: Graduate standing in the Neuroscience program.

This course is to be used by graduate students fulfilling the teaching requirements for the Ph.D. in Neuroscience. Students may choose between in-lab or lecture-based instruction for the course. For in-lab, the student will be paired with an underclassman or rotation student and serve as their primary instructor. For lecture-based, the student will function as a discussion leader and lecturer in a limited number of class sessions. For either track, the student will meet with the faculty they are assisting and participate in individual progress meetings and development of research products (in-lab) or preparation of presentation materials and tests (lecture-based). Each student will be evaluated by the faculty mentor and by the students in the lab or class taught. (Same as NEUS 800.) Prerequisite: Graduate standing in Neuroscience.

Lectures and discussion on ethical issues in the conduct of a scientific career, with emphasis on practical topics of special importance in molecular-level research in the chemical, biological, and pharmaceutical sciences. Topics will include the nature of ethics, the scientist in the laboratory, as author, grantee, reviewer, employer/employee, teacher/ student, and citizen. Discussions will focus on case histories. This course is open only to distance education students. Graded on a satisfactory/unsatisfactory basis. (Same as MDCM 801, P&TX 801, PHCH 801 and PHCH 802.)

This course is designed for graduate students and will fulfill the first written exam requirement for the Ph.D. in Neuroscience. The student will research and write a six page literature review by choosing a topic provided by the faculty. Prerequisite: Graduate standing in the Neuroscience Program.

This course is designed for graduate students and will fulfill the second written exam requirement for the Ph.D. in Neuroscience. The student will research and write a twelve page literature review by choosing a topic provided by the faculty. Prerequisite: Graduate standing in the Neuroscience Program.

Original investigations at an advanced level in the areas of neuroscience. The research by each student will be performed in the laboratory of one of the faculty mentors of the graduate program in Neuroscience. Prerequisite: Graduate standing in the Neuroscience program.

Team-taught, in-depth neuroscience course focusing on normal and diseased brain function at the molecular, cellular and systems levels. Lectures and discussions will emphasize current issues in neuroscience research. (Same as ANAT 846, PHCL 846, PHSL 846 and NEUS 846.) Prerequisite: Permission of the course director.

Development of the nervous system from early induction to the development of learning and memory. Topics include: Induction; Cellular Differentiation; Axon Growth and Guidance; Target Selection; Cell Survival and Growth; Synapse Formation; Synapse Elimination; and Development of Behavior. (Same as ANAT 847, PHSL 847, and NEUS 847.) Prerequisite: Advanced Neuroscience (ANAT 846; NURO 846; PHSL 846) or consent of instructor.

An in-depth coverage of pathogenic mechanisms in neurological diseases; cellular and molecular responses to brain injury and disease, neuroinflammatory diseases (e.g., multiple sclerosis), neurodegenerative diseases (e.g., Alzheimer's, Parkinson's, Huntington's, amyotrophic lateral sclerosis, and prion diseases), neurogenetic diseases (e.g., lysosomal and peroxisomal disorders, Down's syndrome and fragile X), trauma, stroke, and viral diseases (e.g., HIV encephalitis). (Same as ANAT 848, PHCL 848, PHSL 848, and NEUS 848.) Prerequisite: Advanced Neuroscience (ANAT 846, PHCL 846 or PHSL 846) or an equivalent course and consent of instructor.

Hours and credit for this course to be arranged with the mentor. Independent investigation of a research problem in neuroscience, but of limited scope. Prerequisite: Graduate standing in the Neuroscience program and consent of mentor/instructor.

Hours and credit for this course to be arranged with the mentor. Conduct of original investigation in neurosciences. Prerequisite: Graduate standing in the Neuroscience program post-oral comprehensive examination and consent of mentor/instructor.

The pharmacology series covers the mechanisms by which drugs interact with living organisms. An integrative emphasis will be placed on understanding the molecular basis of drug action with respect to modifying the pathophysiology of specific disease states. Topics in P&TX 630 include, general principles of pharmacokinetics and pharmacodynamics, pharmacology of the nervous system, biotechnology drugs, pharmacogenomics, and vitamins. Prerequisite: Students must be admitted to the school of Pharmacy to enroll in this course. Students must have successfully completed BIOL 646.

The pharmacology series covers the mechanisms by which drugs interact with living organisms. An integrative emphasis will be placed on understanding the molecular basis of drug action with respect to modifying the pathophysiology of specific disease states. Prerequisite: Students must have first year professional standing in the School of Pharmacy. Students must have successfully completed P&TX 630.

The pharmacology series covers the mechanisms by which drugs interact with living organisms. An integrative emphasis will be placed on understanding the molecular basis of drug action with respect to modifying the pathophysiology of specific disease states. Prerequisite: Students must be admitted to the school of Pharmacy to enroll in this course. Students must have successfully completed P&TX 630 and P&TX 631.

The pharmacology series covers the basic principles of the immunology, inflammation, and targeted drugs used to regulate the immune response. In addition, basic concepts of infectious diseases and their therapeutics are discussed. Prerequisite: Students must have second year professional standing in the School of Pharmacy. Students must have successfully completed P&TX 630, P&TX 631 and P&TX 632.

General principles of toxicology, treatment, and management of accidental poisoning, and current topics of interest. Prerequisite: Students must have third year professional standing in the School of Pharmacy. Students must have successfully completed P&TX 630, P&TX 631, P&TX 632 and P&TX 633.

The objective of this course is to provide students with an opportunity to read, examine, and report on a broad array of topics relevant to diabetes and obesity. Students will be given broad latitude to propose topics of interest to them within the area of diabetes and obesity. The format of the course will be group presentations. Groups of 3 students will identify a topic of interest to them in the field of diabetes and obesity, prepare a 30 min presentation and deliver it to the class for discussion. Prerequisite: Students must be admitted to the school of Pharmacy and have successfully completed P&TX 630 to enroll in this course.

Neurodegenerative diseases, such as Alzheimer's and Parkinson's diseases, are associated with older age and/or enhanced oxidative stress. The possible causes for the development and progression of these diseases with relation to current research in the field will be discussed. Additionally, a summary of available and suggested future treatments will be given. Prerequisite: Students must be admitted to the school of Pharmacy and have successfully completed P&TX 630 to enroll in this course.

Several addictions will be discussed including addictions to alcohol, cocaine, methamphetamine, gambling, and others as time permits. The physiology, biochemistry, pharmacology and available treatments for these addictions will be reviewed. The role of pharmacotherapies will be discussed, particularly as they relate to the molecular basis of addiction. Behavioral and psychological approaches also will be examined. Prerequisite: Completion of P&TX 632 or special permission from faculty.

This course provides information regarding commonly used psychotropic medications, or any drug that affects brain activities associated with mental processes and behavior. This includes, but are not limited to, the categories of antipsychotics, mood stabilizers, anti-anxiety (anxiolytics), antidepressants, and stimulants. The range of topics from basic biology to drug-drug interactions will be explored in the course. Groups of three students will identify a topic of interest to them in the field of psychotropic drugs and affect, mood, or behavior, prepare a 30 min presentation, and deliver it to the class for discussion. Prerequisite: P&TX 630.

The human gut is home to about 100 trillion microorganisms (bacteria, archaea, viruses, fungi, and protozoa) that form a complex and dynamic ecosystem – the gut microbiota. This course will explore host-gut microbe interactions across the lifespan, the role of the gut microbiota in health (e.g., immune system development, resistance to opportunistic pathogens, metabolism, gut-brain axis, behavior), the association between a disrupted microbiota (dysbiosis) and numerous diseases (e.g., inflammatory bowel disease, asthma and allergy, obesity, diabetes, cardiovascular and kidney disorders, depression, and neurodegeneration), and the bidirectional interactions between gut microbes and drugs and other chemicals. The profound effects of diet on microbial diversity will be examined in depth. Approaches to maintaining or restoring a healthy gut microbiota will be considered. Prerequisite: Students must have second-year professional standing in the School of Pharmacy.

Original research on a laboratory problem of limited scope. This course cannot count toward pharmacology and toxicology requirements in the School of Pharmacy. Prerequisite: Consent of instructor.

Original library review of a limited special topic in pharmacology and toxicology. The student will write a review in his or her report. This course may count toward pharmacology and toxicology requirements in the School of Pharmacy. Prerequisite: P&TX 635 and consent of instructor.

A course designed to assist doctoral students in the biomedical sciences in their professional development by providing presentations, discussions, and practical experiences related to career planning. Topics include diverse career opportunities and expectations of each, preparation of vitae/resumes and other elements of a successful job search, writing scientific papers and dealing with editors, developing programmatic research programs, balancing professional obligations, advancing through promotions, and related topics. Prerequisite: Graduate standing in Pharmacology and Toxicology Program.

A detailed study of the foundational concepts and leading-edge discoveries in biochemistry and molecular biology that underlie the actions and effects of drugs and toxicants with particular relevance to human disease and new therapeutic strategies. The interconnectedness and integration of seemingly disparate pathways and regulatory mechanisms will be emphasized. The technologies and experimental approaches used in biochemical pharmacology and toxicology will be illustrated. Topics may vary from year to year depending on recent advances in the field. The course will involve a combination of lectures and discussions with an emphasis on critically reading and analyzing primary research papers. Students will be evaluated on the basis of oral presentations and take-home problem sets. Prerequisite: Graduate standing in Pharmacology and Toxicology Program. Two semesters of undergraduate biochemistry with molecular biology.

A detailed study of the fundamentals of autonomic nervous system, central nervous system, and their pharmacology. Prerequisite: Permission of the course director.

A detailed study of the fundamentals of cardiovascular system, renal system and their pharmacology. Prerequisite: Graduate standing in Pharmacology and Toxicology Program.

A detailed study of the fundamentals of inflammation, treatment for infectious disease and gastrointestinal pharmacology. Prerequisite: Graduate standing in Pharmacology and Toxicology Program.

A detailed study of the fundamentals of endocrinology and associated pharmacology. Prerequisite: Graduate standing in Pharmacology and Toxicology Program.

Experimental approaches to understanding mechanism of drug action. Use of drugs as tools to understand functioning of biological systems will also be stressed. The focus is on the different types of receptor systems and signaling pathways. Topics will include: pharmacokinetics, pharmacodynamics, G-protein linked receptors, ion channels, nuclear receptors and kinase signaling cascades. Prerequisite: Graduate standing in Pharmacology and Toxicology Program.

A detailed study of the fundamentals of the experimental methods used in a modern toxicology laboratory. Prerequisite: Graduate standing in Pharmacology and Toxicology Program.

An introduction to the basic principles of biochemistry and molecular biology as well as pharmacokinetics and pharmacodynamics of drug action. Additional lectures will introduce students to principles of genomics, transgenic technologies and microscopy. Prerequisite: Graduate standing in the Distance M.S. Program in Pharmacology and Toxicology.

A detailed study of the fundamental concepts of endocrinology with an emphasis on the pathophysiologic details of diabetes and the pharmacology of treatment. Brief discussions on hypothalamic/pituitary, reproductive, thyroid and adrenal endocrinology and pharmacology will be presented. Prerequisite: Graduate standing in the Distance M.S. Program in Pharmacology and Toxicology and completion of P&TX 750.

A detailed study of the fundamental concepts of the autonomic nervous system, central nervous system, and select diseases of the CNS and their pharmacology. Prerequisite: Graduate standing in the Distance M.S. Program in Pharmacology and Toxicology and completion of P&TX 750.

A detailed study of the fundamental principles of the cardiovascular system, renal system and their associated pharmacology. Prerequisite: Graduate standing in the Distance M.S. Program in Pharmacology and Toxicology and completion of P&TX 750.

This course is a detailed study of the fundamental concepts of immunology, inflammatory-related diseases and immunopharmacology, infectious diseases and gastrointestinal pharmacology. Prerequisite: Graduate standing in the Distance M.S. Program in Pharmacology and Toxicology and completion of P&TX 750.

A detailed study of the fundamentals of the toxicology, drug transformations and the mode of toxicity of various drug classes. Prerequisite: Graduate standing in the Distance M.S. Program in Pharmacology and Toxicology and completion of P&TX 750.

A detailed study of the fundamental concepts of receptor pharmacology with an emphasis on the structures, functions, and pharmacology of G-protein signaling, ion channels, nuclear receptors and kinase signaling. Prerequisite: Graduate standing in the Distance M.S. Program in Pharmacology and Toxicology and completion of P&TX 750.

A detailed study of fundamental concepts of pharmacogenomics - how genes and genetic variation determine interindividual differences in drug response - experimental approaches, select gene-drug examples, translation from research to clinical use, and ethical, legal and social implications. Prerequisites: Graduate standing in the Distance M.S. Program in Pharmacology and Toxicology.

Lectures and practical experience in written and oral communication skills, featuring various types of scientific writing. Prerequisite: Graduate standing in the Distance M.S. Program in Pharmacology and Toxicology and completion of at least 4 courses from the P&TX 750 – P&TX 755 series.

An in-depth presentation of the use of optogenetics and two photon imaging in exploring synaptic plasticity in the CNS. Prerequisite: Graduate standing in the Distance M.S. Program in Pharmacology and Toxicology and completion of at least 4 courses from the P&TX 750 – P&TX 755 series.

Students will participate in student-lead journal club discussions and lead one journal club discussion under the mentorship of a faculty member. This is a synchronous course that online students join via video conferencing so students must be available during the regularly scheduled departmental journal club class. Prerequisite: Graduate standing in the Distance M.S. Program in Pharmacology and Toxicology and completion of at least 4 courses from the P&TX 750 – P&TX 755 series.

To satisfy the research requirement for the Distance M.S. program in Pharmacology and Toxicology, the aspiring student must define a research project and prepare a written proposal describing the nature and goals of the project. It is suggested that the student in conjunction with their distance research mentor collaborate in the selection of and the definition of the proposed research. The proposal should be 4 pages (0.5 in margins, 11-12 point Arial, Times Roman or Calibri font) that states the overall goal of the project, the hypothesis to be tested, 2-3 specific aims, a statement of significance and impact of the research and research approach. Prerequisite: Graduate standing in the Distance M.S. Program in Pharmacology and Toxicology, and completion of P&TX 750.

A review of current literature and research in pharmacology and toxicology. Required of all graduate students in the department every fall and spring semester. Graded on a satisfactory/unsatisfactory basis. Prerequisite: Graduate standing in P&TX.

This course is to be used by graduate students fulfilling the teaching requirements for the Ph.D. in pharmacology and toxicology. The student will function as a discussion leader and lecturer in a limited number of class sessions. Each student will meet with the faculty whom he or she is assisting. Prerequisite: Graduate standing in Pharmacology and Toxicology Program.

Lectures and discussion on ethical issues in the conduct of a scientific career, with emphasis on practical topics of special importance in molecular-level research in the chemical, biological, and pharmaceutical sciences. Topics will include the nature of ethics, the scientist in the laboratory, as author, grantee, reviewer, employer/employee, teacher/ student, and citizen. Discussions will focus on case histories. This course is open only to distance education students. Graded on a satisfactory/unsatisfactory basis. (Same as MDCM 801, NURO 801, PHCH 801 and PHCH 802.)

This course is designed for graduate students and will fulfill the first written exam requirement for the Ph.D. in pharmacology and Toxicology. The student will research and write a six page literature review by choosing a topic provided by the faculty. Prerequisite: Graduate standing in Pharmacology and Toxicology Program.

This course is designed for graduate students and will fulfill the second written exam requirement for the Ph.D. in pharmacology and Toxicology. The student will research and write a twelve page literature review by choosing a topic provided by the faculty. Prerequisite: Graduate standing in Pharmacology and Toxicology Program.

This course is intended to be the final course in the program and will be used to complete the literature-based research proposal. Prerequisite: Graduate standing in the Distance M.S. Program in Pharmacology and Toxicology and completion of at least 26 credit hours.

Original investigations at an advanced level in the areas of pharmacology or toxicology or related fields. This research will be performed by graduate students in collaboration with a faculty member. Prerequisite: Graduate standing and consent of instructor.

Original investigations at an advanced level in the areas of pharmacology or toxicology or related fields. This research will be performed by graduate students in collaboration at their place of off-site mentoring in collaboration with the faculty mentor. Prerequisite: Graduate standing in the Online M.S. Program in Pharmacology and Toxicology and consent of KU Pharmacology and Toxicology Faculty Mentor.

Original investigations at an advanced level in areas of pharmacology or toxicology or related fields. This research will be performed by graduate students in collaboration at their place of off-site mentoring in collaboration with the faculty mentor. Prerequisite: Graduate standing in the Distance M.S. Program in Pharmacology and Toxicology and completion of 12 credits in P&TX 785.

Independent investigation of a research problem of limited scope, leading to the preparation of a written Master's Degree thesis. Prerequisite: Graduate standing in the Distance M.S. Program in Pharmacology and Toxicology and completion of 12 credits in P&TX 885.

Independent investigation of a research problem of limited scope, leading to the preparation of a written Master's Degree thesis. Prerequisite: Graduate standing in the On-line M.S. Program in Pharmacology and Toxicology.

Independent investigation of a research problem of limited scope leading to the preparation of a written Master's Degree thesis. Prerequisite: Graduate standing in the Online M.S. Program in Pharmacology and Toxicology.

Hours and credit to be arranged. Independent investigation of a research problem of limited scope. Prerequisite: Graduate standing in Pharmacology and Toxicology Program and consent of instructor.

Hours and credit to be arranged. Original investigation in pharmacology and toxicology. Prerequisite: Consent of instructor.

This course serves as an introduction to modern medication therapy while also discussing critically important historical medications. Students will have the opportunity to explore drug therapy related to many common topics and disease states such as mental health disorders, substance abuse hypertension, diabetes mellitus, asthma, viral and bacterial infections, critical care (e.g., hospital ICU), vaccines, hormones and contraceptives, and pain disorders including the use of opioids. This course is designed for KU students who are interested in pursuing a healthcare career and establishing a pharmacologic foundation for a variety of respective disciplines. This includes but is not limited to: medicine, pharmacy, nursing, physician assistant, physical therapy, occupational therapy, and respiratory therapy.

This course is designed to introduce pharmacy students to the profession of pharmacy, potential career pathways, and available academic and post-doctoral educational opportunities. Additionally, topics such as professionalism, leadership, professional advocacy, empathy, cultural competency, self-directed learning, interprofessional education, and professional communication will be discussed. Students will receive instruction and fulfill the prerequisites for their Introductory Pharmacy Practice Experiences (IPPE) occurring in the summer semesters of the PharmD program.

This course is comprised of a survey of historical highlights of the development of Pharmacy as a discipline. The course will cover early antecedents of pharmacy, development of the discipline in Europe and the United States, the development of professional organizations, standards, education, and literature, economic development, and the pharmacists' contributions to community service, science, and the industry. There will be a mix of some lectures, discussion, assigned readings, and short papers. Prerequisite: Students must have first, second or third year professional standing in the School of Pharmacy.

The Professional Activities Lab curriculum is a team-taught, 6-semester, 10-credit hour laboratory sequence designed to prepare students to perform Entrustable Professional Activities (EPAs) for pharmacy practice prior to milestone examinations and experiential rotations. Lab activities will focus on students' exposure to, hands-on-practice of, and competency of a variety of pharmacy-specific skills. The P1 year will focus on community pharmacy related skills and activities, the P2 year will focus on institutional pharmacy skills, and the P3 year will focus on advanced pharmacy practice skills across multiple settings. As students progress through the 6-semester sequence, they will be expected to increasingly combine physical assessment, communication, patient counseling, and drug information skills, along with applying pharmacotherapy knowledge towards patient-care related activities. A variety of teaching and assessment modalities will be used including but not limited to podcasts, online quizzes, active-learning games, role playing, standardized patients, high-fidelity simulator mannequins, online modules, and traditional exams. Prerequisite: Students must be admitted to the school of Pharmacy to enroll in this course. Students must have first year professional standing in the School of Pharmacy.

The Professional Activities Lab curriculum is a team-taught, 6-semester, 10-credit hour laboratory sequence designed to prepare students to perform Entrustable Professional Activities (EPAs) for pharmacy practice prior to milestone examinations and experiential rotations. Lab activities will focus on students' exposure to, hands-on-practice of, and competency of a variety of pharmacy-specific skills. The P1 year will focus on community pharmacy related skills and activities, the P2 year will focus on institutional pharmacy skills, and the P3 year will focus on advanced pharmacy practice skills across multiple settings. As students progress through the 6-semester sequence, they will be expected to increasingly combine physical assessment, communication, patient counseling, and drug information skills, along with applying pharmacotherapy knowledge towards patient-care related activities. A variety of teaching and assessment modalities will be used including but not limited to podcasts, online quizzes, active-learning games, role playing, standardized patients, high-fidelity simulator mannequins, online modules, and traditional exams. Prerequisite: Students must be admitted to the school of Pharmacy to enroll in this course. Students must have first year professional standing in the School of Pharmacy.

Communicating research plans and experimental finding is a critical skill for health care professionals working in a research environment, and successful communication depends on clarity of thought and careful use of language. This course is intended for 3rd professional (P3) year students who are seeking residencies or fellowships and will need to write research proposals and abstracts, as well as prepare effective posters and presentations. It is an intensive course with multiple writing assignments. Students are expected to participate fully, and individual feedback and guidance on writing will provided by the instructor. Graded on a satisfactory/fail basis. Prerequisite: Students must be admitted to the school of Pharmacy to enroll in this course. Students must be in their third professional year (P3).

The Professional Activities Lab curriculum is a team-taught, 6-semester, 10-credit hour laboratory sequence designed to prepare students to perform Entrustable Professional Activities (EPAs) for pharmacy practice prior to milestone examinations and experiential rotations. Lab activities will focus on students' exposure to, hands-on-practice of, and competency of a variety of pharmacy-specific skills. The P1 year will focus on community pharmacy related skills and activities, the P2 year will focus on institutional pharmacy skills, and the P3 year will focus on advanced pharmacy practice skills across multiple settings. As students progress through the 6-semester sequence, they will be expected to increasingly combine physical assessment, communication, patient counseling, and drug information skills, along with applying pharmacotherapy knowledge towards patient-care related activities. A variety of teaching and assessment modalities will be used including but not limited to podcasts, online quizzes, active-learning games, role playing, standardized patients, high-fidelity simulator mannequins, online modules, and traditional exams. Prerequisite: Students must have first year professional standing in the School of Pharmacy. Students must have successfully completed PHAR 510 and PHAR 512; and current enrollment or successful completion of PHAR 517 and PHPR 661.

Communicating research plans and experimental findings is a critical skill for health care professionals working in a research environment, and a successful oral presentation depends on clear thinking and careful slide design to tell a story. This course is intended for 3rd year professional (P3) pharmacy students who are seeking residency and will need to prepare effective presentations. It is an intensive course with successive slide drafts and presentations. Students are expected to participate fully, and individual feedback and guidance on presentations will be provided by the other students and by the instructor. Graded on a satisfactory/fail basis. Prerequisite: Students must have third year professional standing in the School of Pharmacy. Students must have successfully completed PHAR 514 or consent of instructor.

The Professional Activities Lab curriculum is a team-taught, 6-semester, 10-credit hour laboratory sequence designed to prepare students to perform Entrustable Professional Activities (EPAs) for pharmacy practice prior to milestone examinations and experiential rotations. Lab activities will focus on students' exposure to, hands-on-practice of, and competency of a variety of pharmacy-specific skills. The P1 year will focus on community pharmacy related skills and activities, the P2 year will focus on institutional pharmacy skills, and the P3 year will focus on advanced pharmacy practice skills across multiple settings. As students progress through the 6-semester sequence, they will be expected to increasingly combine physical assessment, communication, patient counseling, and drug information skills, along with applying pharmacotherapy knowledge towards patient-care related activities. A variety of teaching and assessment modalities will be used including but not limited to podcasts, online quizzes, active-learning games, role playing, standardized patients, high-fidelity simulator mannequins, online modules, and traditional exams. Prerequisite: Students must have first year professional standing in the School of Pharmacy. Students must have successfully completed PHAR 510 and PHAR 512; and current enrollment or successful completion of PHAR 515 and PHPR 661.

Exercises that reinforce the concepts taught in pharmacy practice, pharmaceutical chemistry, medicinal chemistry, and pharmacology courses. Includes exercises in compounding, dispensing, and patient counseling. Prerequisite: Students must be admitted to the school of Pharmacy and have successfully completed PHPR 661 and PHAR 515 and PHAR 517 and have successfully completed or be concurrently enrolled in PHPR 662 to enroll in this course.

Exercises that reinforce the concepts taught in pharmacy practice, pharmaceutical chemistry, medicinal chemistry, and pharmacology courses. Includes exercises in compounding, dispensing, and patient counseling. Prerequisite: Students must have second year professional standing in the School of Pharmacy and successfully completed PHPR 662, PHAR 520 and current enrollment or successful completion of PHPR 663.

Exercises that reinforce the concepts taught in pharmacy practice, pharmaceutical chemistry, medicinal chemistry, and pharmacology courses. Includes exercises in compounding, dispensing, and patient counseling. Prerequisite: Students must be admitted to the school of Pharmacy and have successfully completed PHPR 663 and PHAR 525 and have successfully completed or be concurrently enrolled in PHPR 664 to enroll in this course.

Exercises that reinforce the concepts taught in pharmacy practice, pharmaceutical chemistry, medicinal chemistry, and pharmacology courses. Includes exercises in compounding, dispensing, and patient counseling. Prerequisite: Students must have third year professional standing in the School of Pharmacy. Students must have successfully completed PHAR 530 and PHPR 664; and current enrollment or successful completion of PHAR 537.

This laboratory course will allow students to develop clinical assessment skills necessary in the provision of pharmaceutical care to patients with a variety of disease states. Students will combine physical assessment skills, patient counseling skills, and pharmacotherapy knowledge and apply this information to patient care related activities in various clinical settings. Students will apply their skills using various practice models that include medication therapy management, collaborative drug therapy management, and interprofessional healthcare teams. The lab component will require students to meet between 1:00 to 5:00PM on either Monday, Tuesday, or Wednesdays. Prerequisite: Students must have third year professional standing in the School of Pharmacy. Students must have successfully completed PHAR 530 and PHPR 664; and current enrollment or successful completion of PHAR 535.

A required four credit hour experiential course involving 160 hours of on-site experiential education. The course is designed to provide the student pharmacist with exposure to the practice of pharmacy in either an independent community or chain pharmacy in either a rural or urban setting within the state of Kansas. Graded on a satisfactory/unsatisfactory basis. Prerequisite: Students must be admitted to the school of Pharmacy to enroll in this course. Students must have successfully completed PHAR 500.

A required four credit hour experiential course years involving 160 hours of on-site experiential education. The course is designed to provide the student pharmacist with exposure to the practice of pharmacy in an institutional health-system (hospital) environment in either a rural or urban setting within the state of Kansas. Graded on a satisfactory/unsatisfactory basis. Prerequisite: Students must have second or third year professional standing in the School of Pharmacy.

This course is an interdepartmental elective focusing on advanced clinical decision-making within the field of infectious diseases. Utilizing clinical infectious disease cases based off of real-life patients, students will assess and make therapeutic recommendations via team-based active-learning exercises. These activities aim prepare students for advanced pharmacy practice and residency experiences in acute care settings with complicated and challenging patients, by providing students hands-on instruction in reading and assessing patient data including laboratory values and radiology reports, following patient progress over multiple days and adjusting patent care plans based on new unforeseen data, writing infectious diseases-specific SOAP notes, orally presenting patients using presentation styles expected for 4th year APPE rotations and residency rotations, and using basic scientific principles when determining appropriate courses of patient care. Additional professional preparation in "soft skills" will be provided. Prerequisite: Students must be admitted to the school of Pharmacy to enroll in this course. Students must be in their third professional year (P3).

This course explores many cancer-related topics, including non-pharmacologic treatment modalities, complications of cancer and its treatment, supportive care issues, and precision medicine. It also reviews current cancer screening and prevention guidelines and cancer research. Various cancers are discussed, such as myeloma, pediatric cancers, and cancers of the bladder, kidneys, ovaries, and testes. Prerequisite: Students must have third year professional standing in the School of Pharmacy and have successfully completed MDCM 626.

This elective course will focus on the understanding and active enrollment of patients into Medicare prescription drug benefit (Part D). Students will mainly focus on the understanding of Medicare eligibility, benefits, formulary requirements, and the administration of benefits. Students will also participate in community outreach which may focus on underserved patients. Prerequisite: Students must be admitted to the school of Pharmacy to enroll in this course. Must be a 2nd or 3rd professional year standing in the School of Pharmacy.

This course provides the fundamentals for developing a medical vocabulary. The student will develop the ability to understand, define and utilize medical terminology and abbreviations used in patient care.

This elective course is designed for the learner to explore many of the clinical considerations employed when caring for the aging patient within our health care system. The course will be devoted to exploring perceptions of the older adult patient, learning how the aging process can impact patient care, and identifying the role of the pharmacist in enhancing this care through the 5M's of geriatric care. Prerequisite: Students must have second or third year professional standing in the School of Pharmacy.

This course introduces the student to medication safety and the technology as well as the tools used in error prevention. The student will also learn about adverse drug events including both medication errors and adverse drug reactions in hospital and retail pharmacy settings. Prerequisite: Students must have second or third year professional standing in the School of Pharmacy.

This course is designed for students interested in developing a business plan. Most pharmacists will have an opportunity to develop a new service, product line or even start a new business venture in their careers. Students need to know how to create a formal business plan and how to present the plan to decision makers. The course will cover the basic components and rationale of creating a formal a business plan. When finished students will be expected to have created a written business plan and will present their creation to the class. In this manner, students will gain experience in developing an idea into a plan. Prerequisite: Students must be admitted to the school of Pharmacy.

This course will review a variety of diseases including: multiple sclerosis, hepatitis C and autoimmune conditions (psoriasis, ulcerative colitis, etc) and the specialty medications used to treat these conditions. Specialty pharmacy accreditation standards as well as topic discussions reviewing many issues facing the specialty pharmacy industry will be discussed. Guest speakers from different specialty pharmacies in the greater Kansas City area will also present information on their career experiences. Prerequisite: Students must have second or third year professional standing in the School of Pharmacy.

This course will expose students to conditions frequently encountered in pediatric care. Students will further develop knowledge and skills necessary to provide appropriate pediatric care in institutional, ambulatory, and community practice settings. The course will involve interactive lectures followed by case-based learning to promote student application of knowledge to relevant clinical situations. Prerequisite: Students must be admitted to the School of Pharmacy and must be in their 3rd professional year.

This course reviews pertinent problems traveling entails and services pharmacists can provide for traveling patients. The course will involve interactive lectures followed by case-based learning to promote student application of knowledge to relevant clinical situations. Following the completion of this course, students should be able to recognize the need to establish travel health services, the role of pharmacists in these services, identify the commonly encountered disease states and problems for travelers, and what components comprise travel health by utilizing comprehensive knowledge, skills and resources necessary to establish and deliver successful travel health service. Prerequisite: Students must be admitted to the School of Pharmacy and must be in their 2nd or 3rd professional year. Students must have successfully completed the APhA Pharmacy-Based Immunization Delivery program.

This is an elective course focusing on advanced clinical decision making within the field of critical care. Using clinical critical care cases, student will work as a team to assess and make therapeutic recommendations through problem-based learning exercises. These activities aim to prepare students for advanced pharmacy practice and residency experiences in acute care settings by providing instruction in application of primary literature to patient cases, following patient progress through emergency department and intensive care settings, and oral presentation of evidence-based patients cases. Additionally, students will participate in an acute care interprofessional simulation. Prerequisite: Students must be admitted to the School of Pharmacy and must be in their 3rd professional year.

This elective course will explore many of the clinical and practical considerations employed when caring for patients in the ambulatory care setting. The course will expose the learner to a variety of topics that impact the pharmacist's role in this practice setting, including collaborative practice agreements, patient case evaluations, communication skill development, and practice evaluation. The course will be facilitated by the ambulatory care practice group at The University of Kansas Health System and will prepare the student for advanced pharmacy practice and residency experiences in the ambulatory care setting. Prerequisite: P2 or P3 standing in the School of Pharmacy.

This course is team-taught by KU clinical faculty with the support of pharmacy residency program directors, residency preceptors, and pharmacy residents. This course is designed to increase knowledge, interest, and confidence amongst students about residency training; identify and develop the skills necessary to apply to residency programs; and increase the number of students obtaining residency positions upon graduation. Prerequisite: Third year professional standing in the School of Pharmacy and instructor consent.

This elective course is designed to provide learners with the opportunity to gain further clinical and practical considerations when caring for patients with psychiatric disorders and substance use disorders. The course will expose the learner to a variety of topics that impact the pharmacist's role in treating patients with psychiatric disorders. This course will help prepare students who are interested in the field of psychiatry. Prerequisite: Successful completion of PHPR 662.

This advanced elective course will focus on clinical application of vancomycin, aminoglycoside, and anti-fungal therapeutic drug monitoring utilizing multiple-day real patient cases. The course format will consist of alternating week(s) of online learning via calculation assignments and in-person class debriefing discussions. Prerequisite: P3 Standing in School of Pharmacy.

This course introduces the foundations of the pharmaceutical industry, by first introducing the drug development process from investigational molecules to FDA approval and beyond. A variety of departments within the pharmaceutical industry will be explored, including but not limited to: Clinical development and operations, regulatory affairs, medical affairs and information, market access, sales and commercial operations, and pharmacovigilance. Additionally, pharmaceutical industry fellowships will be introduced, and projects will aid in the development of materials to assist in applications, interviews, and success in PhRMA. Prerequisite: P2 and P3 students enrolled at the KU School of Pharmacy are eligible to enroll in this course.

This survey course is motivated, designed and taught by current experts and practicing pharmacists in managed care. The instructors have real-world experience and subject matter expertise. The course is designed to provide students with current information in managed care and expose students to unique, non-traditional pharmacist opportunities. Students will be exposed to the current practice of each pharmacist and explore the spectrum of managed care pharmacy. Clinical and pharmacy management, regulatory and practice topics will be covered in the course. The US health care system is complex. A solid understanding of how managed care pharmacy practice works benefits all stakeholders and especially students. Having completed the course students will be better equipped to practice pharmacy in any professional setting. Prerequisite: P2 standing in the School of Pharmacy or above to take this elective course. Students need to have completed PHPR 619.

This TeamSTEPPS Level 1 experience will introduce interprofessional students to the basic concepts of interprofessional collaboration including values and ethics, roles and responsibilities of healthcare team members, and interprofessional communication tools using the evidence-based national curriculum of TeamSTEPPS. Upon completion of this training experience students will be able to 1) demonstrate a work ethic with individuals of other professions to maintain a climate of mutual respect and shared values; 2) define the role of health professions (including your own) within the healthcare system; 3) identify opportunities to seek expertise of health professionals to improve communication and healthcare; and 4) acquire basic TeamSTEPPS communication tools to effectively use with healthcare teams. Graded on a satisfactory/unsatisfactory basis. Prerequisite: Students must be admitted to the school of Pharmacy to enroll in this course. Student must have P1 standing in the School of Pharmacy.

This TeamSTEPPS Level 2 experience will provide interprofessional students opportunities to apply key knowledge and skills gained in FIPC I, through role-play and case-based learning. Students will apply their knowledge of roles and responsibilities of healthcare team members and interprofessional communication tools and continue learning with, from, and about students from other professions. Upon completion of this training experience students will be able to: 1) engage diverse healthcare professionals who complement one's own professional expertise, as well as associated resources, to develop strategies to meet specific patient care needs; 2) choose effective communication tools and techniques, including information systems and communication technologies, to facilitate discussions and interactions that enhance team function: and 3:) engage other health professionals appropriate to the specific care situation--in shared patient-centered problem-solving. Graded on a satisfactory/unsatisfactory basis. Prerequisite: Students must be admitted to the school of Pharmacy to enroll in this course. Student must have P2 standing in the School of Pharmacy and successfully completed PHPR 661.

This TeamSTEPPS Level 3 experience will provide interprofessional students opportunities to demonstrate key knowledge and skills gained in FIPC I and II, through simulation. Students will demonstrate their interprofessional communication skills, including specific opportunities to utilize TeamSTEPPS tools. Students will also demonstrate their teamwork abilities by working with interprofessional students during the simulation. Upon completion of this training experience students will be able to: 1) demonstrate communicating effectively with other health professionals about a patient case; 2) exhibit teamwork skills with an interprofessional healthcare team; and 3) utilize key TeamSTEPPS tools with an interprofessional healthcare team. Graded on a satisfactory/unsatisfactory basis. Prerequisite: Students must have third year professional standing in the School of Pharmacy. Students must have successfully completed PHPR 663.

The final year of the Doctor of Pharmacy program is spent participating in pharmacy practice experience rotations. These consist of nine, one-month rotations, in various health care settings. Such practice settings may include a variety of acute care, ambulatory care, managed care, hospital and community practice sites. Each rotation provides an academically structured environment that enables the student to gain practical experience under the guidance of a practicing health care professional. The purpose of providing pharmacy students with a pharmacist role model is to foster the development of both professional confidence as well as competence. These practice-based experience settings encourage the student to apply their didactic education to clinical problem solving. Both clinical and distributive pharmacy services will be integrated in these experiences for optimal learning. This course is graded using an "Excellent", "Satisfactory", or "Unsatisfactory" grading basis.

The final year of the Doctor of Pharmacy program is spent participating in pharmacy practice experience rotations. These consist of nine, one-month rotations, in various health care settings. Such practice settings may include a variety of acute care, ambulatory care, managed care, hospital and community practice sites. Each rotation provides an academically structured environment that enables the student to gain practical experience under the guidance of a practicing health care professional. The purpose of providing pharmacy students with a pharmacist role model is to foster the development of both professional confidence as well as competence. These practice-based experience settings encourage the student to apply their didactic education to clinical problem solving. Both clinical and distributive pharmacy services will be integrated in these experiences for optimal learning. This course is graded using an "Excellent", "Satisfactory", or "Unsatisfactory" grading basis.

The final year of the Doctor of Pharmacy program is spent participating in pharmacy practice experience rotations. These consist of nine, one-month rotations, in various health care settings. Such practice settings may include a variety of acute care, ambulatory care, managed care, hospital and community practice sites. Each rotation provides an academically structured environment that enables the student to gain practical experience under the guidance of a practicing health care professional. The purpose of providing pharmacy students with a pharmacist role model is to foster the development of both professional confidence as well as competence. These practice-based experience settings encourage the student to apply their didactic education to clinical problem solving. Both clinical and distributive pharmacy services will be integrated in these experiences for optimal learning. This course is graded using an "Excellent", "Satisfactory", or "Unsatisfactory" grading basis.

The final year of the Doctor of Pharmacy program is spent participating in pharmacy practice experience rotations. These consist of nine, one-month rotations, in various health care settings. Such practice settings may include a variety of acute care, ambulatory care, managed care, hospital and community practice sites. Each rotation provides an academically structured environment that enables the student to gain practical experience under the guidance of a practicing health care professional. The purpose of providing pharmacy students with a pharmacist role model is to foster the development of both professional confidence as well as competence. These practice-based experience settings encourage the student to apply their didactic education to clinical problem solving. Both clinical and distributive pharmacy services will be integrated in these experiences for optimal learning. This course is graded using an "Excellent", "Satisfactory", or "Unsatisfactory" grading basis. Prerequisite: Students must have fourth year professional standing in the School of Pharmacy.

The final year of the Doctor of Pharmacy program is spent participating in pharmacy practice experience rotations. These consist of nine, one-month rotations, in various health care settings. Such practice settings may include a variety of acute care, ambulatory care, managed care, hospital and community practice sites. Each rotation provides an academically structured environment that enables the student to gain practical experience under the guidance of a practicing health care professional. The purpose of providing pharmacy students with a pharmacist role model is to foster the development of both professional confidence as well as competence. These practice-based experience settings encourage the student to apply their didactic education to clinical problem solving. Both clinical and distributive pharmacy services will be integrated in these experiences for optimal learning. This course is graded using an "Excellent", "Satisfactory", or "Unsatisfactory" grading basis. Prerequisite: Students must have fourth year professional standing in the School of Pharmacy.

The final year of the Doctor of Pharmacy program is spent participating in pharmacy practice experience rotations. These consist of nine, one-month rotations, in various health care settings. Such practice settings may include a variety of acute care, ambulatory care, managed care, hospital and community practice sites. Each rotation provides an academically structured environment that enables the student to gain practical experience under the guidance of a practicing health care professional. The purpose of providing pharmacy students with a pharmacist role model is to foster the development of both professional confidence as well as competence. These practice-based experience settings encourage the student to apply their didactic education to clinical problem solving. Both clinical and distributive pharmacy services will be integrated in these experiences for optimal learning. This course is graded using an "Excellent", "Satisfactory", or "Unsatisfactory" grading basis. Prerequisite: Students must have fourth year professional standing in the School of Pharmacy.

The final year of the Doctor of Pharmacy program is spent participating in pharmacy practice experience rotations. These consist of nine, one-month rotations, in various health care settings. Such practice settings may include a variety of acute care, ambulatory care, managed care, hospital and community practice sites. Each rotation provides an academically structured environment that enables the student to gain practical experience under the guidance of a practicing health care professional. The purpose of providing pharmacy students with a pharmacist role model is to foster the development of both professional confidence as well as competence. These practice-based experience settings encourage the student to apply their didactic education to clinical problem solving. Both clinical and distributive pharmacy services will be integrated in these experiences for optimal learning. This course is graded using an "Excellent", "Satisfactory", or "Unsatisfactory" grading basis. Prerequisite: Students must have fourth year professional standing in the School of Pharmacy.

The final year of the Doctor of Pharmacy program is spent participating in pharmacy practice experience rotations. These consist of nine, one-month rotations, in various health care settings. Such practice settings may include a variety of acute care, ambulatory care, managed care, hospital and community practice sites. Each rotation provides an academically structured environment that enables the student to gain practical experience under the guidance of a practicing health care professional. The purpose of providing pharmacy students with a pharmacist role model is to foster the development of both professional confidence as well as competence. These practice-based experience settings encourage the student to apply their didactic education to clinical problem solving. Both clinical and distributive pharmacy services will be integrated in these experiences for optimal learning. This course is graded using an "Excellent", "Satisfactory", or "Unsatisfactory" grading basis. Prerequisite: Students must have fourth year professional standing in the School of Pharmacy.

The final year of the Doctor of Pharmacy program is spent participating in pharmacy practice experience rotations. These consist of nine, one-month rotations, in various health care settings. Such practice settings may include a variety of acute care, ambulatory care, managed care, hospital and community practice sites. Each rotation provides an academically structured environment that enables the student to gain practical experience under the guidance of a practicing health care professional. The purpose of providing pharmacy students with a pharmacist role model is to foster the development of both professional confidence as well as competence. These practice-based experience settings encourage the student to apply their didactic education to clinical problem solving. Both clinical and distributive pharmacy services will be integrated in these experiences for optimal learning. This course is graded using an "Excellent", "Satisfactory", or "Unsatisfactory" grading basis. Prerequisite: Students must have fourth year professional standing in the School of Pharmacy.

The final year of the Doctor of Pharmacy program is spent participating in nine pharmacy practice experience rotations (PHPR 601-609). PHPR 610 is reserved for students requiring a remedial experiential rotation. This course is graded using an "Excellent", "Satisfactory", or "Unsatisfactory" grading basis. Prerequisite: Students must have fourth year professional standing in the School of Pharmacy.

A course to foster an understanding of economic, financial and outcome principles that drive the demand and supply of medical care in the US. Economic logic behind decisions made by patients, physicians, hospitals, managed care organizations, and governments will be covered. Students completing this course should be able to identify the drivers of the health economy, identify different types of pharmacoeconomic evaluations, critically analyze pharmacoeconomic and outcome literature, and apply economic principles to pharmaceutical care. Prerequisite: Students must have third year professional standing in the School of Pharmacy.

A course designed to provide knowledge and skills to effect efficient and effective pharmacy management. This will include foundations in financial management, inventory control, purchasing, cost-effective drug utilization, quality management, pharmacoeconomics, and human resource management.

Introduction to pharmacy services within health-system pharmacies with an emphasis on medication distribution systems, parenteral and sterile products, clinical pharmacy practice and other services. Prerequisite: Must be accepted to the Pharmacy program.

This course is an introduction to the organization, financing, and delivery of health care services with a focus on the U.S. health care system. Course content addresses the following questions: how do we evaluate the health care sector, where is health care provided, how is health care financed, what are the characteristics of health care providers (individuals and institutions), what influences the performance of the health care sector, and what lies in the future for health care delivery. The purpose of the course is to prepare pharmacy students for non-clinical aspects of their practice sites. Enrollment limited to pharmacy majors. Prerequisite: Students must have first year professional standing in the School of Pharmacy.

This course provides an introduction to the fundamentals of law and ethics as they apply to the practice of pharmacy. Course sessions will focus on ethical expectations of the profession, principles and issues in medical and pharmacy ethics, and laws that govern medication dispensing.

A course developed to increase students' knowledge and understanding of laws that regulate the pharmacy profession. Prerequisite: Students must be admitted to the school of Pharmacy to enroll in this course. Students must be in their third professional year standing in the School of Pharmacy and eligible for APPE rotations at the conclusion of the semester.

Pharmacy profession has a unique and critical opportunity and responsibility to contribute to the improvement of population health. Public health is a broader discipline that encompasses population health with a variety of other areas, including but not limited to epidemiology, cultural competence, health promotion, disease prevention, and drug safety. Pharmacoepidemiology is the application of the principles of epidemiology to the study of medications and their effects. Considerations are centered on providing beneficial or adverse effects of medication use in large populations and making relevant inferences from essential analytical research designs used in public health. Using population-based-care approach, students will adopt and fulfill public health roles and activities. This course provides a broad introduction to the principles of pharmacoepidemiology and public health with a focus on applications in the field of pharmacy. Prerequisite: Students must be admitted to the school of Pharmacy to enroll in this course. Students must have P3 standing in the School of Pharmacy.

This course reviews study designs and statistical methods commonly used in primary medical literature. In collaboration with other courses in the curriculum, this course prepares students to interpret and apply primary literature during patient care, collect and analyze data, and maintain clinical competency throughout their professional career in pharmacy. Following completion of this course, students should be able to identify or select appropriate research methods and study designs; collect, summarize and interpret research data; understand basic statistical concepts; identify or select appropriate statistical tests for hypothesis testing; conduct and interpret the results of statistical tests; and evaluate the validity and reliability of published research studies.

This course will review the fundamental tools used to identify drug information in primary, secondary and tertiary resources. In addition, students will learn to assess published literature, utilize electronic resources, and learn to formulate a response to drug information questions. Following completion of this course, students will be able to understand the strengths and weaknesses of the drug information resources and to apply drug information skills to clinical practice relevant to patient care. Prerequisite: Successful completion of PHPR 629 and Fifth year standing (P3 student).

A course designed for the study of special topics in pharmacy practice. A research paper will be required. Prerequisite: Consent of instructor.

A course dealing with the clinical applications of drug knowledge to patient care. Drug interactions and patient counseling techniques will be covered. Over-the-counter medications and herbals will also be a significant portion of the course. Prerequisite: Students must be admitted to the school of Pharmacy to enroll in this course. Student must have first year professional standing in the School of Pharmacy and successfully completed PHAR 510, PHAR 512 and concurrent enrollment or successfully completed PHAR 515 and PHAR 517.

A course dealing with the clinical applications of drug knowledge to patient care. Disease and drug knowledge will be applied to the design and monitoring of therapeutic treatment plans for patients. Prerequisite: Students must be admitted to the school of Pharmacy and have successfully completed PHPR 661 and PHAR 515 and PHAR 517 to enroll in this course.

A course dealing with the clinical applications of drug knowledge to patient care. Disease and drug knowledge will be applied to the design and monitoring of therapeutic treatment plans for patients. Prerequisite: Students must be admitted to the school of Pharmacy to enroll in this course. Student must have second year professional standing in the School of Pharmacy and successfully completed PHPR 662 and PHAR 520.

A course dealing with the clinical applications of drug knowledge to patient care. Disease and drug knowledge will be applied to the design and monitoring of therapeutic treatment plans for patients. Prerequisite: Students must be admitted to the school of Pharmacy and have successfully completed PHPR 663 and PHAR 525 to enroll in this course.

A course dealing with the clinical applications of drug knowledge to patient care. Disease and drug knowledge will be applied to the design and monitoring of therapeutic treatment plans for patients. Prerequisite: Students must have third year professional standing in the School of Pharmacy. Students must have successfully completed PHAR 530 and PHPR 664.

This laboratory course will allow students to develop clinical assessment skills necessary in the provision of pharmaceutical care to patients with a variety of disease states. Students will combine physical assessment skills, patient counseling skills, and pharmacotherapy knowledge and apply this information to patient care related activities in various clinical settings. Students will apply their skills using various practice models that include medication therapy management, collaborative drug therapy management, and interprofessional healthcare teams. The lab component will require students to meet between 1:00 to 5:00 PM on either Monday, Tuesday, or Wednesdays. In addition, there is a required Thursday discussion section. A detailed schedule of lab meeting dates and times will be provided in the syllabus. Prerequisite: Students must be admitted to the School of Pharmacy to enroll in this class. Students must pass PHPR 664 to be eligible to complete PHPR 670.

Students will conduct original research in a laboratory, educational, or clinical research setting under the supervision of department faculty. Prerequisite: Students must be admitted to the School of Pharmacy to enroll in this class.

A course designed to give the graduate student a practical experience in areas of professional communications such as administrative proposals, grants, letters, memos, poster presentations, and written papers. The course focuses on the different kinds of communications required to relate to other health care professionals. Prerequisite: Consent of instructor.

The course will provide students with an overview and appraisal of the "state-of-the-art" in the evaluation of health care programs and services (with a special emphasis on pharmaceutical programs, services, and products). The purpose of the course is to provide the student with the tools to conduct economic rather than general evaluation of health care programs and services. There will be some discussion of theoretical concepts, but the major emphasis will be on practical methodological issues in economic evaluation of pharmaceutical programs. The course integrates the perspectives of pharmaceutical and health care technology assessment, managed care, outcomes research, and public health. The main topics covered in the course include: cost, cost-minimization, cost-effectiveness, cost-utility, and cost-benefit analyses.

Research reports, reviews, and/or presentations on the current status of various aspects of pharmacy practice. Prerequisite: Consent of instructor.

Advanced Institutional Pharmacy Services (I) includes activities involving administrative and behavioral science techniques to manage 'the business of pharmacy practice'. Topics and information will be borrowed from the disciplines of business management, accounting, economics, finance, marketing, operations research and applied to the practice of pharmacy. Upon completion of the course, students should be able to explain, understand and apply pharmacy practice management techniques in the following general areas: business management, pharmacy financial management and operations management. Prerequisite: Consent of instructor.

Advanced Institutional Pharmacy Services (II) includes activities involving administrative and behavioral science techniques to manage 'the business of pharmacy practice'. Topics and information will be borrowed from the disciplines of business management, accounting, economics, finance, marketing, operations research and applied to the practice of pharmacy. Upon completion of the course, students should be able to explain, understand and apply pharmacy practice management techniques in the following general areas: human resource management, clinical services management, specialty pharmacy services and technology management. Prerequisite: Consent of Instructor.

Original investigation in the area of pharmacy practice. Prerequisite: Consent of instructor.